RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
Pvt1
RNA ID
RNA Type
lncrna
Alteration Pattern
patched2 demethylation
Species
mus musculus
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
NA
Pathway
HEDGEHOG SIGNALING PATHWAY
PubMed ID
Title
Long non-coding RNA PVT1 activates hepatic stellate cells through competitively binding microRNA-152
Year
2016
Function
"Pvt1 epigenetically down-regulates ptch1 expression via competitively binding mir-152, contributing to emt process in liver fibrosis."